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Effects of the Physical Fitness on Serum Klotho Levels in Healthy Population

Effects of the Physical Fitness on Serum Klotho Levels in Healthy Population: Response and Adaptation

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03509818
Acronym
CoFiKSa
Enrollment
85
Registered
2018-04-26
Start date
2018-03-21
Completion date
2019-03-26
Last updated
2019-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Population

Keywords

Klotho, Exercise, Physical Fitness

Brief summary

Exercise program in serum Klotho levels

Detailed description

This study aims to analiyze the effects of acute exercise in serum Klotho levels attending physical fitness in healthy population

Interventions

OTHERplyometric exercise

acute plyometric exercise

OTHERAerobic exercise

acute aerobic exercise

Sponsors

Universidad Europea de Madrid
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
SINGLE (Subject)

Intervention model description

Description of the sample

Eligibility

Sex/Gender
MALE
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* healthy people between 20 and 45 years old

Exclusion criteria

* acute and chronic disease, people who take medication and supplements, smoker.

Design outcomes

Primary

MeasureTime frameDescription
Change in serum Klotho levelsBaseline and one hourChange from baseline to acute exercise session

Secondary

MeasureTime frameDescription
Change in Body CompositionBaselineThe age in years; height in centimeters (tallimeter Ano Sayol SL, Barcelona, Spain); weight in kilograms (Inbody 720, Microcaya) and we can derive from this data the variable of Body Mass Index (BMI) calculated as weight (kg)/height (m2).
Change in Body Composition, Body muscle mass IndexBaselineFor determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)
Change in Cardiorespiratory Fitness VO2maxBaselineFor this Variable All people Will perform a exercise test on treadmill (Tecnhogym run race 1400HC; Gambettola, Italy), in this way we determinate the VO2max. Through the modifies Balke protocol. The gas Exchange data Will measured breath by breath using open circuit spirometry and specific face mask for Fitmate, Cosmed; Vmax 29C, Sensormedics machine.
Change in Body Composition, Total Muscle MassBaselineFor determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)
Change in Body Composition, Visceral Fat Index.BaselineFor determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA). This value is really important to determine a cardiovascular risk.
Change in Body Composition, % of Fat MassBaselineFor determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026