Obesity, Quality of Life, Urinary Incontinence, Urodynamics
Conditions
Brief summary
In the population of obese women, the prevalence of urinary incontinence (UI) is around 70%. It was shown in the literature that weight loss by bariatric surgery allowed a significant improvement in the symptoms and impact on the quality of life of the IU. However, no prognostic factor for recovery has yet been identified and the pathophysiological mechanisms underpinning this improvement are not fully elucidated. The main objective of this study is to highlight the urodynamic changes associated with the improvement of the symptom and quality of life scores in a population of incontinent obese women before and after bariatric surgery.
Interventions
OTHERExploratory pathophysiology Study
Urodynamic tests before and after bariatric surgery in obese incontinent women before and after bariatric surgery
Sponsors
University Hospital, Caen
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
The research protocol will be proposed to all patients requiring bariatric surgery (gastric bypass or sleeve gastrectomy) and describing urinary incontinence according to the definition of the International Continence Society (ICS)
Exclusion criteria
* minors under the age of 18 * pregnant or lactating women * women not speaking French (important to understand and respond to questionnaires) * women who have not given their written consent * neurological diseases, * patients who have benefited from urinary incontinence surgery, prolapse treatment or pelvic surgery at risk of urodynamic modifications (extensive resection of deep endometriosis, pelvic wound surgery, pelvic radiation therapy).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Urodynamic changes after bariatric surgery in obese incontinent women | 24 months | to highlight the changes in urodynamic vesical pressure (cmH2O) associated with the improvement of urinary incontinence after bariatric surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Urinary incontinence symptom improvement after bariatric surgery | 24 months | Changes in ICIQ-SF (International Consultation on Incontinence Questionnaire - Short Form) scores (assessing frequency and quantity of urinary loss, ranging from 0 to 21) after weight loss in incontinent obese women |
| Quality of life improvement after bariatric surgery | 24 months | Measuring changes in Quality of life after weight loss with the Contilife questionnaire which specifically measures the impact of urinary incontinence on quality of life : activity of daily life |
Countries
France
Contacts
Primary ContactAnne-Cécile Pizzoferrato, MD, PhD
Backup ContactAnne Villot, MD
Outcome results
None listed