Revascularization
Conditions
Keywords
immature teeth, necrotic teeth
Brief summary
This clinical study aims to investigate the predictability of revascularization procedure of immature necrotic human permanent teeth with apical periodontitis. The quality of root development (thickness and length) will be assessed radiographically.
Detailed description
All teeth will be disinfected using either triple antibiotic paste (a mixture of metronidazole, ciprofloxacin and amoxicillin mixed with sterile glycole) or non setting calcium hydroxide applied to the pulp space with a sterile lentulospiral and then closed temporarily with a sterile sponge and temporary restoration for 2-3 weeks to allow disinfection of the canals teeth will be reentered under rubber dam isolation and all intracanal medicaments will be washed out from the canal using 10 ml of 2.5% sodium hypochlorite and 20 ml of Ethylene diamine tetra acetic acid (EDTA). Then, a sterile endodontic file will be inserted past the canal terminus into the periapical tissues to induce bleeding to fill the canal space as much as possible and subsequently sealed with a double coronal seal using bioceramic repair material and composite filling. All the teeth will be monitored clinically and radiographically on a biannual basis.
Interventions
PROCEDURETriple paste and induced bleeding
DRUGTriple Paste metronidazole, ciprofloxacin and minocycline mixed with sterile glycol
triple paste of metronidazole, ciprofloxacin and minocycline mixed with sterile glycol
Sponsors
Jordan University of Science and Technology
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Revascularization for immature necrotic permanent teeth with apical periodontitis.
Eligibility
Sex/Gender
ALL
Age
6 Years to 20 Years
Healthy volunteers
Yes
Inclusion criteria
1. Teeth diagnosed with necrotic pulp with/without evidence of apical periodontitis. 2. An immature/open apex. 3. Tooth does not need post and core restoration. 4. Medically healthy patients with no known allergy to used materials.
Exclusion criteria
1. Medically compromised patient, 2. Teeth with periodontal involvement 3. Teeth with vertical root fractures, 4. Non-restorable teeth,
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| complete healing | from start of intervention up to 100 months. | Assess clinically and radiographically absence of symptoms and signs. And evidence for continuation of root development |
Countries
Jordan
Outcome results
None listed