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Does Mixing Alcoholic Drinks Make Hangover Worse?

Does Mixing Alcoholic Drinks Make Hangover Worse? A Randomized Controlled Trial in a Naturalistic Setting

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03506516
Enrollment
35
Registered
2018-04-24
Start date
2016-05-20
Completion date
2018-01-31
Last updated
2018-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol-Related Disorders

Keywords

alcohol, hangover

Brief summary

Does mixing alcohol make hangover worse?

Detailed description

Hangover is the most commonly occurring morbidity associated with heavy drinking. Our aim was to test the hypothesis that mixing alcoholic drinks as compared to drinking one type of alcohol only (beer, wine or spirits) associate with a higher alcohol intake and worse hangover.

Interventions

DIETARY_SUPPLEMENTMixing alcohol

Alcoholic beverages, different types

DIETARY_SUPPLEMENTSingle type alcohol

Alcoholic beverages, different types

Sponsors

Zealand University Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* written and oral consent * minimum 18 years old * participating in Danish Health Research Retreat in Turkey 2016 * will consume alcoholic beverages

Exclusion criteria

* underage * will not consume alcoholic beverages

Design outcomes

Primary

MeasureTime frameDescription
Acute Hangover Severity Scale (AHSS)BaselineAHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.

Secondary

MeasureTime frameDescription
Number of drinksBaselineTotal number of drinks defined as 12 g of alcohol consumed during evening
Acute Hangover Severity Scale (AHSS) 2after 4 hoursAHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.
Acute Hangover Severity Scale (AHSS) 3after 8 hoursAHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026