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A New Prognostic Scoring System for Spontaneous Ruptured Hepatocellular

A New Prognostic Scoring System for Spontaneous Ruptured Hepatocellular Carcinoma: A Retrospective Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03504358
Enrollment
129
Registered
2018-04-20
Start date
2005-01-01
Completion date
2017-12-31
Last updated
2018-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rupture, Spontaneous

Keywords

surgery, scoring system, hepatocellular carcinoma, homogeneity and discriminatory ability, survival

Brief summary

Develop a new scoring system for HCC patients with tumor rupture.

Detailed description

There has been no special prognostic scoring system for HCC patients with tumor rupture in the literature. In this work, we obtained all survival risk factors of ruptured HCC patients who underwent partial hepatectomy using multivariable Cox regression analysis. Furthermore, we develop and validate a new postoperative scoring system for patients with spontaneous HCC rupture based on the these results.

Interventions

PROCEDURELiver resection

Partial hepatectomy comprised single or multiple hepatic resections aiming at excising all visible malignant tissue.

Sponsors

Huazhong University of Science and Technology
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
15 Years to 75 Years

Inclusion criteria

* Received partial hepatectomy; with Child A or B liver function.

Exclusion criteria

* Without complete data;loss of follow-up; had reveived repeated transcatheter arterial chemoembolization before rupture; received non-radical resection.

Design outcomes

Primary

MeasureTime frameDescription
Overall survival3 yearsOverall survival after partial hepatectomy

Secondary

MeasureTime frameDescription
Disease-free survival3 yearsRecurrence-free survival after partial hepatectomy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026