Physiological Effect of TCC on Glucose Metabolism
Conditions
Keywords
Tai Chi Chuan, insulin resistance, cholesterol, endothelin-1
Brief summary
The short term effects of TCC exercise are the significant increase in serum insulin and insulin resistance, and the significant decrease in serum TC, HDL-C, ET-1 and insulin sensitivity in TCC practitioners. TCC might be benefit the health of its practitioners through the regulation of lipid and glucose metabolism and endothelial function.
Detailed description
Tai Chi Chuan (TCC) has been shown to be beneficial to the health. However, its effects on lipid and glucose metabolism are not fully understood. This study investigated the short term effect of TCC exercise on lipid and glucose metabolism and endothelial function in TCC practitioners. Twenty-one TCC practitioners and nineteen normal controls were included in this study. The hemodynamics, serum insulin, indices of insulin resistance/sensitivity, serum endothelin-1 (ET-1), blood lipids and aldosterone before and 30 min after a rest or a session of classical Yang's TCC exercise were compared.
Interventions
BEHAVIORALClassical Yang's TCC exercise
Sponsors
Taipei Veterans General Hospital, Taiwan
Changhua Christian Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Intervention model description
Twenty-one TCC practitioners and nineteen normal controls were included in this study. The hemodynamics, serum insulin, indices of insulin resistance/sensitivity, serum endothelin-1 (ET-1), blood lipids and aldosterone before and 30 min after a rest or a session of classical Yang's TCC exercise were compared.
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* TCC practitioners in a TCC training center in Taiwan over 50 years of age * Healthy subjects without TCC experience over 50 years of age
Exclusion criteria
* Subjects who had major cardiopulmonary disease * Subjects who have diabetes mellitus, renal or liver disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in quantitative insulin sensitivity check index | before and 30 minutes after the completion of TCC exercise | change in insulin sensitivity due to TCC |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in serum total cholesterol | before and 30 minutes after the completion of TCC exercise | change in serum total cholesterol due to TCC |
| change in homeostasis model assessment-estimated insulin resistance | before and 30 minutes after the completion of TCC exercise | change in insulin resistance by TCC |
Other
| Measure | Time frame | Description |
|---|---|---|
| change in serum insulin | before and 30 minutes after the completion of TCC exercise | change in serum level of insulin due to TCC |
| change in serum triglyceride | before and 30 minutes after the completion of TCC exercise | change in serum level of triglyceride due to TCC |
| change in serum aldosterone | before and 30 minutes after the completion of TCC exercise | change in serum level of aldosterone due to TCC |
| change in serum endothelin-1 | before and 30 minutes after the completion of TCC exercise | change in serum level of endothelin-1 due to TCC |
| change in serum low density lipoprotein | before and 30 minutes after the completion of TCC exercise | change in serum level of low density lipoprotein due to TCC |
| change in serum high density lipoprotein | before and 30 minutes after the completion of TCC exercise | change in serum level of high density lipoprotein due to TCC |
Countries
Taiwan
Outcome results
None listed