Metabolic Disturbance
Conditions
Keywords
Metabolic syndrome, Obesity
Brief summary
Despite exercise training decrease blood fasting glicaemy in 'average' terms, there is a wide inter-individual variability after exercise training explored mainly in adults but not in adults with prediabetes comorbidities. Thus, is yet unknown the effects and influence of the concurrent training (CT) eliciting responders (R) and non-responders (NR) cases (i.e., percentage of subjects who experienced a non-change/worsened response after training in some metabolic outcomes).
Interventions
BEHAVIORALEndurance training plus resistant training
CT in women with prediabetes and co-morbidities associated. Exercise will be performed at three sessions per week. Post statistical analyses will be including analyses by the 2 groups proposed. All sessions will be supervised by an exercise physiologist during 20-weeks.
Sponsors
Universidad de Los Lagos
Healthcare Center Tomas Rojas
Universidad del Rosario
Universidad Santo Tomas
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)
Intervention model description
Behavioral
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 59 Years
Healthy volunteers
Yes
Inclusion criteria
* Written informed consent. * Interested in improving health and fitness.
Exclusion criteria
* Cardiovascular contraindications to exercise, * History of stroke, asthma or chronic obstructive pulmonary disease, * Muscle-skeletal disorders, and * Smoking. * A compliance rate to the exercise program ≥ 70% was required for the participants in the intervention group to be included in the statistical analyses.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Fasting glucose | Baseline and 20-weeks immediately after the interventions ends | Change from Baseline in fasting glucose |
| Lipoproteins | Baseline and 20-weeks immediately after the interventions ends | Change from baseline in lipoproteins |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Fat mass | Baseline and 20-weeks immediately after the interventions ends | Change from Baseline in fat mass |
| Lean mass | Baseline and 20-weeks immediately after the interventions ends | Change from Baseline in lean mass |
| Body mass | Baseline and 20-weeks immediately after the interventions ends | Change from Baseline in body mass |
| Six minutes walking test | Baseline and 20-weeks immediately after the interventions ends | Change from Baseline in six minutes walking test |
| Heart rate at rest | Baseline and 20-weeks immediately after the interventions ends | Change from Baseline in heart rate at rest |
| Waist circumference | Baseline and 20-weeks immediately after the interventions ends | Change from Baseline in waist circumference |
Countries
Chile
Outcome results
None listed