Molecular Modulation of the Growth Plate

Status

Enrolling by invitation

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03501589

Enrollment

100

Registered

2018-04-18

Start date

2013-10-31

Completion date

2026-10-31

Last updated

2025-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Growth Plate Injury

Brief summary

The researchers are trying to identify molecular mechanisms that control growth plate mediated limb growth and identify agents that can be used to enhance or slow growth.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Skeletally immature children/adults undergoing surgical procedures where growth plate cartilage is removed as a normal part of their procedure; or patients undergoing surgical procedures where bone is removed as a normal part of their procedure.

Exclusion criteria

* Skeletally mature children/adults

Design outcomes

Primary

Measure	Time frame	Description
RNA expression	End of Study (1/2019	Measure RNA levels in growth plate tissue samples (ng/mL)

Countries

United States

Outcome results