Effect of Topical Anesthesia on Patient's Pain Discomfort and Radial Artery Spasm in Transradial Catheterization

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03501212

Enrollment

120

Registered

2018-04-18

Start date

2019-04-27

Completion date

2019-06-30

Last updated

2018-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radial Artery Spasm

Brief summary

This study evaluate topical anaesthesia application for 30 minutes before tranradial catheterization during cardiac catheterization can reduce pain and decrease radial artery spasm

Detailed description

The incidence of Radial artery spasm (RAS) has varied from 5-30% RAS refers to friction between the artery and wires or guide catheters accompanied by a subjective feeling of pain. EMLA anesthetic ointment (AO-Astra Zeneca) is an emulsion of lidocaine 2.5% and prilocaine 2.5% in a ratio of 1:1 by weight Previous study showed that EMLA cream can increase the success rate of femoral cannulation in children.

Interventions

DRUGTopical Anesthetic

EMLA Cream 2.5 gr applied to both wrists

DRUGPlacebo

Placebo Cream 2.5gr applied to both wrist

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Patients age \>18 years. * Patients who was schedule to performed coronary angiogram

Exclusion criteria

Previous ipsilateral transradial approach Raynaud's syndrome ESRD History of sensitivity to local anesthetics Non-palpable redial pulse Abnormal Barbeau's test Local site infection Patient's refusal

Design outcomes

Primary

Measure	Time frame	Description
Radial pain assessed during artery puncture	30 min	Record pain by visual analog score sub-scale 0(no pain)-10(max pain)

Secondary

Measure	Time frame	Description
Radial pain assessed 30 min after sheath removal	4 hr post procedure	Record pain by visual analog score
Number of puncture attempts	imediate post procedure	Number of puncture attempts
Occurrence of radial artery spasm	during and post procedure up to 1 years	NuNumber of radial artery spasm

Countries

Thailand

Contacts

Primary ContactAnuwat Rintaravitoon

Rintaravitoon@hotmail.com+66869920022

Backup ContactNakarin Sansanatudh

+666444755

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026