Effects of Maternal Obesity on Offspring Brain Development

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03499587

Enrollment

Registered

2018-04-17

Start date

2018-03-21

Completion date

2026-12-27

Last updated

2025-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

The goal of this study is to see if there are negative effects of maternal obesity during pregnancy on offspring's brain development.

Detailed description

This study will recruit pregnant women who are either obese or normal weight and otherwise healthy. We will measure their body composition, food intake and other characteristics during pregnancy. When their babies are born, we will evaluate the brain development of their babies using magnetic resonance imaging and electroencephalography at age two weeks. We will then compare the findings and see if their are differences.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* BMI 18.5-25 or \>30 with early OB visit medical records accessible * singleton pregnancy * about 36wks of pregnancy * at least 18 years of age

Exclusion criteria

* hypertension, diabetes, or other preexisting medical conditions * medications known to influence fetal growth * recreational drugs, nicotine or tobacco use of alcohol use while pregnant * pregnancy conception with assisted fertility treatment * medical complications developed during pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Determine whether maternal obesity correlates with abnormal brain development in newborns	2 weeks	Brain will be imaged at 2wks using an MRI

Countries

United States

Outcome results