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Screening for Atherotic Plaques by Ultrasound for Assessing Cardiovascular Risk

Prevalence of Atherosclerotic Carotid and/or Femoral Plaques in Patients Without Known Cardiovascular Disease and at Low-risk for Major Cardiovascular Events (AGLA/GLSA Score) Visiting a Private Primary Healthcare Practice in Switzerland

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03499496
Enrollment
22
Registered
2018-04-17
Start date
2016-01-15
Completion date
2016-09-04
Last updated
2018-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerosis of Artery

Keywords

plaques detection by ultrasound

Brief summary

Cardiovascular disease is a common diagnosed and treated condition in private practices of primary health care. There is growing evidence that atherosclerotic plaques as predictors for stroke and heart attack are more prevalent than expected based on the clinical score in people with low risk for stroke and heart attack . Diagnosing atherosclerotic plaques can help to decide if a lipid lowering therapy should be prescribed even if the clinical risk score is low or on the other hand if they can be observed even in high lipid levels.

Detailed description

Both common and proximal internal carotid arteries and both common femoral arteries (including bifurcations) were screened by ultrasound in patients who came for a check-up to a primary care practice with no known cardiovascular disease and low risk for stroke and heart attack according to the AGLA/GSLA risk score which is mostly used in Switzerland. All patients agreed and gave written informed consent to be included in this study. Presence of plaques was defined as a focal carotid intima-media thickness \>0.5 cm on ultrasound. Screening was performed by a medical doctor (DP) certified for the procedure using the following ultrasound system: Toshiba Nemio XG, probe 7.5 MhZ.

Interventions

DIAGNOSTIC_TESTultrasound guided detection of atherosclerotic plaques

screening by ultrasound of atherosclerotic plaques

Sponsors

Cabinet de Medecine Interne Générale Demetrio Pitarch
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
41 Years to 72 Years
Healthy volunteers
Yes

Inclusion criteria

* low cardiovascular risk assessed by the AGLA/GSLA-score

Exclusion criteria

* cardiovascular disease

Design outcomes

Primary

MeasureTime frameDescription
Prevalence of plaques in cardiovascular low risk population1 yearNumber of participants with the presence of carotid and/or femoral atherosclerotic plaques diagnosed via ultrasound (defined as a focal intima-media thickness \>0.5 cm on ultrasound).

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026