Azathioprine in Recurrent Implantation Failure

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03498703

Enrollment

Registered

2018-04-17

Start date

2018-04-25

Completion date

2019-07-01

Last updated

2019-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracytoplsmic Sperm Injection, In Vitro Fertilization, Recurrent Implantation Failure

Brief summary

Azathioprine increase pregnancy rate in patients with recurrent implantation failure

Interventions

DRUGAzathioprine Pill

Azathioprine increase pregnancy rate in cases with recurrent implantaion failure

DRUGPlacebo Oral Tablet

Placebo tablets

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 39 Years

Healthy volunteers

Yes

Inclusion criteria

* age: 20-39 * previous 3 or more failed ivf

Exclusion criteria

* intrauterine anomalies * chronic systemic illness * chronic pelvic conditions * sensitivety to azathioprine

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy rate	2 weeks

Secondary

Measure	Time frame
Side effects	2 weeks

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026