Cystic Fibrosis, Primary Ciliary Dyskinesia
Conditions
Brief summary
Cytobacteriological examination of sputum and bacteriological sampling in the middle meatus.
Interventions
DIAGNOSTIC_TESTMiddle meatus aspirations and sputum
Bacterial genotype sequencing analysis will be performed in patients with bacteriological concordance between upper and lower airways.
Sponsors
Centre Hospitalier Intercommunal Creteil
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
6 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients over 6 years old * Patients with cystic fibrosis or primary ciliary dyskinesia. * Patients capable of performing an expectorations * Patients having been informed of the research, having received the information note and not having opposed the research
Exclusion criteria
\- Refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of bacterial colonization of the upper and lower airway | 1 day |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| bacteriological concordance | 1 day | bacteriological concordance of upper airways (VAS) and lower (VAI) between patients with cystic fibrosis and those with primary ciliary dyskinesia. |
| bacteria genotype | 1 day | Compare the genotype of bacteria present in both VAS and VAI. |
| bacteriological concordance in children | 1 day | Subgroup analysis (group \<18 years old) |
| bacteriological concordance in adult | 1 day | Subgroup analysis (adult group) |
Countries
France
Outcome results
None listed