Transpharyngeal Doppler Sonography for Cerebral Perfusion Monitoring

Evaluation of Transpharyngeal Doppler Sonography as a Cerebral Monitoring Tool in Cardiac Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03494413

Acronym

TaPaS

Enrollment

Registered

2018-04-11

Start date

2018-07-10

Completion date

2019-05-02

Last updated

2019-05-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Perfusion

Brief summary

This prospective interventional study investigates transpharyngeal sonography (TPS) as an additional neuromonitoring strategy to assess cerebral perfusion during cardiovascular surgery. In the first part of the study the investigators will investigate the feasibility of TPS for visualization of aortic arch branches including the innominate and the carotid arteries in patients undergoing cardiac surgery with cardiopulmonary bypass. In the second part the investigators plan to adopt the investigators previous experiences on TPS to a selected population of patients undergoing ascending aortic and/or arch repair in hypothermic circulatory arrest (HCA).

Interventions

DIAGNOSTIC_TESTTranspharyngeal Doppler sonography (TPS)

Usage of transpharyngeal Doppler to assess cerebral perfusion during cardiovascular surgery

DIAGNOSTIC_TESTConventional colour-coded Duplex sonography (CDS)

Usage of conventional colour-coded Duplex sonography (CDS) to assess cerebral perfusion during cardiovascular surgery

Study design

Allocation

NON_RANDOMIZED

Intervention model

SEQUENTIAL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Cardiovascular Surgery * Age \> 18 yrs * Informed Consent

Exclusion criteria

* Contraindication for TPS * Carotid artery stenosis

Design outcomes

Primary

Measure	Time frame	Description
Accuracy of cerebral flow velocity measurement	intraoperative phase, expected to be ca. 4 hours	Cerebral blood flow velocity measurements will be performed with transpharyngeal Doppler sonography (TPS) and conventional colour-coded Duplex sonography (CDS). Doppler flow velocities (obtained at the same intraoperative phase and at the same time) will be compared between TPS and CDS TPS and different Doppler techniques.

Secondary

Measure	Time frame	Description
Hypothermic Circulatory Arrest	intraoperative phase, expected to be ca. 4 hours	Doppler flow velocities (obtained with both methods in the Phase of hypothermic circulatory arrest - intraoperatively) will be compared between TPS and CDS TPS and different Doppler techniques.

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026