Non Invasive Electrical Impedance Technology (EIT) for Diagnosing Liver Diseases Severity

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03492879

Enrollment

210

Registered

2018-04-10

Start date

2018-05-15

Completion date

2019-05-30

Last updated

2018-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Liver Disease, Fibrosis, Liver, Non-Alcoholic Fatty Liver Disease

Brief summary

The aims of this study are to assess the performance of the non-invasive Electrical Impedance Technology (EIT) in evaluating the liver fibrosis stage in patients with chronic liver diseases, in comparisons with a liver biopsy and/or Shear wave elastography and Liver Ultrasonography. The second aim is comparing between Liver Ultrasonography and Electrical Impedance Technology (EIT) to quantify the hepatic steatosis grade in patients with Non Alcoholic Fatty Liver Disease (NAFLD) .

Detailed description

The study will include 210 patients with chronic liver diseases. Relevant clinical data such as sex, age, weight, height, alcohol intake, medical history and routine lab results will be collected. The study will include three groups: 1. Patients with indication for liver biopsy will undergo a routine liver biopsy and also routine liver Ultrasonography, Shear wave elastography and Electrical Impedance Technology (EIT) (70 patients). 2. Patients with chronic liver diseases will undergo routine liver Ultrasonography, Shear wave elastography and Electrical Impedance Technology (EIT) (70 patients). 3. Patients with Non Alcoholic Fatty Liver Disease will undergo routine liver Ultrasonography, Shear wave elastography and quantification of liver steatosis using the Electrical Impedance Technology (EIT) (70 patients).

Interventions

DEVICEEIT Technology

Electrical Impedance Technology is a non-invasive imaging method who is being tested for evaluation of liver fibrosis stage

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients with chronic liver diseases

Exclusion criteria

* Patients who don't have chronic liver diseases

Design outcomes

Primary

Measure	Time frame	Description
Evaluating the liver fibrosis stage using Electrical Impedance Technology (EIT)	Each technology will be performed once in 1 year	Comparing EIT fibrosis stage result to fibrosis stage result of validated thechnologies

Contacts

Primary ContactAvishag Hassid, MA

avishag.hassid@sheba.health.gov.il+972-35307176

Backup ContactZiv Ben-Ari, MD

ziv.ben-ari@sheba.health.gov.il+972-35307176

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026