Ovarian Reserve in Patients With Psoriasis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03492632

Enrollment

Registered

2018-04-10

Start date

2017-10-25

Completion date

2018-07-03

Last updated

2018-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anti Mullerian Hormone, Ovarian Reserve, Psoriasis

Keywords

psoriasis, Anti mullerian hormone, ovarian reserve, antral follicle count

Brief summary

Psoriasis is a common autoimmune disease. It affects women of all ages including reproductive years. Autoimmune diseases including psoriasis are linked to premature ovarian reserve. This study aims to measure serum hormones including FSH,LH,E2,PRL and AMH (indicators of ovarian reserve) in women with and without psoriasis.

Detailed description

Psoriasis is a common autoimmune disease. It affects women of all ages including reproductive years. Almost 75% of patients are diagnosed before the age of 40. There is also increased evidence on autoimmune disease and their link to premature ovarian failure.Ovarian reserve is important for the reproductive period. The measurements of serum hormones including follicle stimulating hormone (FSH),luteinizing hormone (LH),prolactin (PRL), estradiol (E2) and anti-mullerian hormone (AMH) will give us an idea about the ovarian reserve. The investigators aim is to measure ovarian reserve parameters in patients newly diagnosed with psoriasis and to compare them to healthy controls. Serum FSH,LH,E2,PRL and AMH will be measured on the 3rd day of the cycle.The serum hormone levels will be compared between women with psoriasis and women without psoriasis

Interventions

OTHERHormone panel

Blood sampling on the 3rd day of menstrual cycle for the measurement of serum FSH,LH,PRL,E2 and AMH hormone levels.

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Reproductive age group women: 18-40 years * Women diagnosed with psoriasis (case group) * Women without psoriasis (control group)

Exclusion criteria

* Women with PCOS (polycystic ovary syndrome) * history of ovarian surgery * Body mass index (BMI) over 30 * Women with other autoimmune diseases including Hashitomo thyroiditis * Women with family history of premature ovarian insufficiency (POI) * Women with infertility * Psoriasis using systemic drugs including steroids and immunosuppressive therapy.

Design outcomes

Primary

Measure	Time frame	Description
to compare serum AMH levels between the two groups	1 day	Serum AMH levels will be measured (using ELISA) and compared between the two groups

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026