Spinal Diseases
Conditions
Brief summary
The researchers are trying to identify molecular mechanisms that control spine deformity and degenerative changes that can be used for therapeutic strategies.
Detailed description
Discarded surgical material from spinal procedures is collected. RNA analysis and other tests on the tissue is performed to determine markers of pathologic disease and to develop pharmacologic treatment strategies for pediatric spinal disorders.
Interventions
OTHERWaste tissues are collected at the time of spinal surgery.
This is a single visit study. Waste tissues are collected at the time of spinal surgery.
Sponsors
Mayo Clinic
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Children and adults undergoing surgical procedures where spinal tissues are removed as a normal part of their procedure. Material from adults may be collected as a control group.
Exclusion criteria
* Surgeries where spinal tissues are not being removed.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| RNA expression | Baseline | Measure RNA levels in spinal tissues samples (ng/mL) |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORA.Noelle Larson, MD
Mayo Clinic
Outcome results
None listed