Double Filtration Plasmapheresis (DFPP) and Lipid Metabolism

Double Filtration Plasmapheresis (DFPP) Improves Lipid Profile and Platelet Function in Hyperlipidemia Patients

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03491956

Enrollment

Registered

2018-04-09

Start date

2018-02-01

Completion date

2021-04-01

Last updated

2021-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

DFPP and Platelet Function

Brief summary

Little clinic trials showed that Double Filtration Plasmapheresis (DFPP) could improve lipid metabolism, however, whether DFPP can improve platelet function and recover Endothelial function is unknown. In this study, we try to confirm the hypothesis that DFPP can improve endothelial function in hyperlipidemia patients.

Interventions

DEVICEDFPP

Lipid levels,platelet function，and platelet RNA sequencing in hyperlipidemia patients before and after DFPP

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

1. hyperlipidemia

Exclusion criteria

1. Severe liver and kidney dysfunction 2. Severe cardiopulmonary insufficiency 3. tumor 4. pregnancy

Design outcomes

Primary

Measure	Time frame	Description
lipid levels	1 year	reduce in lipid levels

Secondary

Measure	Time frame	Description
Platelet RNA sequencing	1 year	whether the RNA sequencing of platelet changed ?

Countries

China

Contacts

Primary ContactHuimin Jin, doctor

hmjgli@163.com13917232915

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 15, 2026