Brugada Syndrome
Conditions
Keywords
Ajmaline test
Brief summary
In this study the investigators analyse echocardiographic images before and during Ajmaline test. The purpose is to know if any echocardiographic modifications are present during either negative or positive Ajmaline testing.
Detailed description
The diagnosis of Brugada Syndrome is made when a type 1 pattern is present on the electrocardiogram (ECG), either spontaneously or after administration of a sodium channel blocker. For pathofysiological understanding, the investigators will analyse echocardiography images before and during the administration of Ajmaline. Comparing echocardiographies before and during negative Ajmaline test, will allow the investigators to indentify the effect of Ajmaline administration on cardiac function. The comparison between images of negative and positive Ajmaline tests will expose differences related to the occurence of a type 1 ECG.
Interventions
DRUGAjmaline test
Administration of Ajmaline
Sponsors
Universitair Ziekenhuis Brussel
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* \>17 years old * clinical indication for Ajmaline test
Exclusion criteria
* History of right ventricular outflow tract ablation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Speckle tracking strain measurement | 1 day at the time of enrollment | Cardiac function assessed by speckle tracking peak strain and peak strain dispersion |
Countries
Belgium
Contacts
Primary ContactEsther Scheirlynck, MD
Backup ContactIngrid Lemoine
Outcome results
None listed