Tonsillectomy
Conditions
Brief summary
morbidity after tonsillictomy remains asignificant problem therefore they recommend prophylactic antibiotics to reduce it.in the other hand, the overuse of antimicrobial agents can lead to antimicrobial resistance ,adverse drug events,and unnecessary cost.so,the effectiveness and necessity of antibiotic following tonsillictomy needs to be studied .
Interventions
after tonsillectomy half of our patients will receive Amoxicillin /clavulanate for one week and the other half will not receive it.
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
1 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
200 patients who are scheduled for tonsillectomy with or without adenoidectomy, and their age are less than 18 years old of either gender will be included in our study
Exclusion criteria
* 1-Patients age ≥ 18 years. 2-Trials in which antibiotics was administrated locally or used in the immediate preoperative period (within seven days before surgery). 3\. Medical comorbidity requiring treatment with antibiotics e.g. Rheumatic heart disease 4-Patients undergoing the following procedures: 1. Unilateral tonsillectomy or biopsy. 2. Tonsillectomy for known carcinoma. 3. Tonsillectomy in conjunction with palatal surgery. 4. Hot tonsillectomy for tonsillar abscess
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| compare the morbidity after tonsillectomy between the group which receive antibiotics and the other group which not receive antibiotics | 2 years | A questionnaire will be given to the parents on discharge to fill in the type of post-tonsillectomy morbidity of main concern including: fever, secondary bleeding, number of days with throat pain and the number of days to resume normal diet, incidence of abdominal pain, nausea & vomiting. |
Contacts
Primary Contactahmed alhussaini, professor
Outcome results
None listed