Study of Microbiota in Bile From Patients With Common Bile Duct Stone During ERCP

ERCP Based Study of Microbiota in Bile From Patients With Common Bile Duct Stone

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03490383

Enrollment

Registered

2018-04-06

Start date

2018-02-16

Completion date

2023-04-01

Last updated

2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholangiopancreatography, Endoscopic Retrograde, Common Bile Duct Calculi, Microbial Colonization

Keywords

ERCP, CBD stone, Microbial Colonization

Brief summary

In this study, investigators will investigate the microbiota of bile in common bile duct stone participants. Three key questions are of concern. The first one is whether there is bacteriria in bile in participants without common bile duct stone. The second one is whether the microbiota of bile is similar with that of gut mucosa in common bile duct stone participants. The third one is whether the bacteria in bile of common bile participants with intact papillar is the same as that of participants underwent sphinctomy.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* CBD tumor or CBD calculi

Exclusion criteria

* contraindication for ERCP

Design outcomes

Primary

Measure	Time frame	Description
microbiota in bile	intraoperative	16s RNA

Countries

China

Outcome results