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Correlation Between the Visual Acuity & the OCT Pattern of Macular Edema Secondary to RVO

Correlation Between the Visual Acuity and the OCT Pattern of Macular Edema Secondary to Retinal Vein Occlusion

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03489915
Enrollment
30
Registered
2018-04-06
Start date
2018-05-01
Completion date
2020-05-31
Last updated
2018-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retinal Vein Occlusion

Brief summary

Correlation between changes observed in OCT and VA in patients with retinal vein occlusion whether the patient's VA improves when macular edema improves in OCT or not ??

Detailed description

Central retinal vein occlusion (CRVO) is a common retinal vascular disorder. Clinically, CRVO presents with variable visual loss; fundus may show retinal hemorrhages, dilated tortuous retinal veins, cotton-wool spots, macular edIn view of the devastating complications associated with the severe form of CRVO, number of classifications were described. All of classifications take into account the area of retinal capillary nonperfusion and development of neovascular complications. CRVO can be divided into 2 clinical types, ischemic and nonischemic. In addition, a number of patients may have an intermediate presentation with variable clinical course. On initial presentation, it may be difficult to classify a given patient, since CRVO may change with time. A number of clinical and ancillary investigative factors are taken into account for classifying CRVO: Nonischemic CRVO is milder form of disease. It may present with good vision, few retinal hemorrhages and cotton-wool spots, no relative afferent pupillary defect, and good perfusion to the retina. Nonischemic CRVO may resolve fully with good visual outcome or may progress to the ischemic type. Ischemic CRVO is the severe form of the disease. CRVO may present initially as the ischemic type, or it may progress from nonischemic. Usually, ischemic CRVO presents with severe visual loss, extensive retinal hemorrhages and cotton-wool spots, presence of relative afferent pupillary defect, poor perfusion to retina, and presence of severe electroretinographic changes. In addition, patients may end up with neovascular glaucoma and a painful blind eye.

Interventions

DEVICEOCT

Assessment of macular edema secondary to retinal vein occlusion usin optical coherence tomography and its correlation with visual acuity

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients with macular edema related to vein occlusion . * Patient's Age above 18 years old . * Patients able to sit on OCT device .

Exclusion criteria

* Significant cataract . * Media opacities as vitreous haemorrhage . * patients with macular edema related to CRVO treated by laser photocoagulation . * patients with glaucoma . * Patients with chronic uveitis.

Design outcomes

Primary

MeasureTime frameDescription
Macular edema assessment5 minutesMacular edema assessed by OCT in microns
Visual acuity assessment5 minutesVisual acuity assessment through Landolt chart

Secondary

MeasureTime frameDescription
Causes of non improvement of visual acuity in patients with resolving macular edema5 minutesTo detect causes of visual non improvement with visual acuity measured through Landolt chart in patients with resolving macular edema measured by OCT device in microns

Contacts

Primary ContactSamir Y Saleh, professor
samir.abouelail@med.au.edu.eg00201003304320
Backup Contactwaleed s Mohamed, lecturer
walidibrahim72@aun.edu.eg002012223971491

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026