Kidney Transplant Infection, Kidney Transplant Rejection
Conditions
Keywords
kidney transplantation, rejection, infection, immunosuppression
Brief summary
All kidney transplant recipients require immunosuppression, the net level of which is difficult to assess. Current practice in assessing immune reactivity is to monitor levels of some immunosuppressive drugs. QuantiFERON Monitor® (QFM) is an in vitro diagnostic test that detects interferon-γ (IFN-γ) release in peripheral blood. Its clinical utility in assessment of the net state of immunosuppression in kidney transplant recipients has not been well studied. The aim of our study is to evaluate the discriminating value of QFM testing results for infection and rejection in a single-centre cohort of kidney transplant recipients.
Interventions
None listed
Sponsors
Clinical Hospital Centre Zagreb
Clinical Hospital Merkur
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Kidney/Liver kidney/Simultaneous pancreas and kidney transplantation
Exclusion criteria
* none
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Infection | throughout the study period (Kidney transplant recipients from 1 day date of tx to 15 years after tx) | Interferon gamma level in patients with infection |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rejection | throughout the study period (Kidney transplant recipients from 1 day date of tx to 15 years after tx) | Interferon gamma levels in patients with rejection |
Countries
Croatia
Contacts
Primary ContactIvan Margeta, MD
Outcome results
None listed