Neural Mechanisms of Decision Making in Hoarding Disorder

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03487224

Acronym

LOSS

Enrollment

Registered

2018-04-03

Start date

2018-07-08

Completion date

2027-05-30

Last updated

2026-08-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hoarding Disorder

Keywords

Hoarding Disorder

Brief summary

The purpose of this study is to understand the neural mechanisms of decision making in hoarding disorder.

Detailed description

Hoarding disorder is a common and disabling disorder that represents a significant public health problem. This study aims to build on current research on decision making by examining these processes in hoarding disorder.

Interventions

DEVICEMRI with fMRI frequency

Functional magnetic resonance imaging or fMRI measures brain activity by detecting changes in blood flow. Participants will do cognitive tasks during fMRI.

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

Identify inclusion criteria. Inclusion criteria for participants diagnosed with HD: 1. ages 18-70 2. primary diagnosis of hoarding disorder 3. sufficient severity of hoarding symptoms 4. stable on psychotropic medications for 1 month prior to study enrollment 5. capacity to provide informed consent 6. ability to tolerate clinical study procedures Inclusion criteria for healthy control participants: 1. ages 18-70 2. capacity to provide informed consent Identify

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
BOLD signal	up to 90 minutes	BOLD signal derived from fMRI

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 14, 2026