Hemoperfusion
Conditions
Brief summary
Sleep disturbance has been long-standing torments in most of patients with maintenance hemodialysis (HD). In this study, we attempted to explore whether long-term hemoperfusion (HP) could improve sleep disorder and increase overall survival rate in HD patients.
Interventions
DEVICEhemoperfusion(HP)
These patients were computer-matched into two groups, involving 100 patients with absolute HD vs. 100 cases with HD+HP.HP was performed 1-2 times/per 2 weeks, and each session lasted for two hours.Self-reported sleep disturbance was evaluated before and after observational time (two-year period), which lasted at least 7 hours based on the recommendations presented by National Institute of Health (NIH). Sleep efficiency (%) was calculated as the ratio of sleep duration to total time in bed, and was multiplied by 100.
Sponsors
Shanghai Pudong Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
1. duration of maintenance HD should be equal or more than 3 months, 2. patient's age should be equal or more than 18 years
Exclusion criteria
\- i) he/she diagnosed with malignant tumors, an active rheumatism, infectious diseases, or a severe heart failure ii) he/she would disagree with the study 3. he/she has received a short-term poor prognosis 4. he/she would be more than 80 years old
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| improvement of self-reported sleep disturbance | 2 years | Analysis of the sleep disturbance by using Pittsburgh Sleep Quality Index (PSQI) questionnaire |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| survival | 2 years | increase overall survival rate |
Outcome results
None listed