Diabetes
Conditions
Keywords
diabetes, high intensity interval training, cardiorespiratory fitness
Brief summary
Aim: To assess whether there are different training effects on glucose concentration and cardiorespiratory parameters of different high-intensity training protocols in patients with type 2 diabetes. Type 2 diabetes is a highly prevalent disease associated with cardiovascular disease leading to high levels of mortality, morbidity and health expenditure, characterized by impaired glucose control during activities and reduced aerobic exercise capacity . Exercise training is the most effective way to improve compliance, reduce blood glucose concentration and increase insulin sensitivity. Training increases muscle capacity, oxidative capacity and glucose transport, peripheral insulin sensitivity is improved. Exercise training with high-intensity interval (resting and exercise period) High Intensity Interval Training (HIIT) is a form of exercise training that has recently been widely used in the management of type 2 diabetes, including short duration high intensity exercise periods and lower severity or passive rest periods. There are different HIIT exercise training programs according to physiological responses in the literature. However, long-term and short-term HIIT training training programs were not compared in terms of their effect on glucose concentration and cardiorespiratory fitness. The aim of this study was to compare the effects of different HIIT exercise training programs so that exercise programs for patients with type 2 diabetes could be planned more effectively.
Detailed description
This study will be participated patients with Type 2 diabetes. Patients' laboratory values, pulmonary function test, respiratory muscle strength, exercise capacity, physical activity level, quality of life will be evaluated. Pulmonary function test will be assesed with spirometer, respiratory muscle strength will be evaluated with mouth pressure. Exercise capacity will be evaluated using six minute walking test, incremental shuttle walk test, cycle ergometer. Muscle oxigeneration will be asssed with wearable lactate threshold predicting device. Physical activity level will be evaluated trial accelerometer. Then, patients will be randomly divided two high intensity interval exercise training groups. First group: short duration high intensity exercise training (Exercise load phase : 30sn %100 Patients performance, rest phase: 120sn %25 patients performance) Second group: Long duration high intensity interval exercise training (Exercise load phase : 4 dk %100 Patients performance, rest phase: 120sn %25 patients performance) All patients will participate three times a week during eight weeks. The muscle oxigeneration, blood glucose consantration, blood pressure, heart rate will be recorded before and after each exercise session. After 8 week, all test will be done again.
Interventions
OTHERShort duration
exercise Short duration high intensity training
OTHERLong duration
exercise Long duration high intensity training
Sponsors
Hacettepe University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 64 Years
Healthy volunteers
No
Inclusion criteria
* diagnosis of type 2 diabetes * aged 18-64 years * patients can walk and cooperative * body mass index is less than 40 kg / m2
Exclusion criteria
Individuals have known lung disease,have undergone any cardiac event or surgery within the past six months, have uncontrolled hypertension, and have diabetic complications such as nephropathy, retinopathy and severe neuropathy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| muscle oxigeneration | Change from baseline muscle oxigeneration at 8 weeks | It is evaluate with wearable lactate threshold device on gastrocinemius |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| pulmonary parameter-Peak expiratory flow | before and after 8 weeks | Peak expiratory flow will be evaluated |
| Respiratory muscle strength | before and after 8 weeks | It is evaluated with mouth pressure |
| The blood glucose consentration | before and after 8 weeks | It is evaluate with sample from blood |
| Functional Exercise capacity | before and after 8 weeks | İt is evaluated with six minute walk test |
| Maximal exercise capacity | before and after 8 weeks | İt is evaluated using with incremental shuttle test |
| Symptom limited maximal exercise capacity | before and after 8 weeks | İt is evaluated with cycle ergometer test |
| Physical activity level | before and after 8 weeks | ıt is assessed using accelerometer |
| Lipit profile- low density lipoprotein cholesterol | before and after 8 weeks | low density lipoprotein cholesterol wiil be assesed |
| Lipit profile- trigliseride | before and after 8 weeks | trigliseride wiil be assesed |
| pulmonary parameter-Forced vital capacity | before and after 8 weeks | Forced vital capacity will be evaluated |
| pulmonary parameter-Forced vital capacity in the first second | before and after 8 weeks | Forced vital capacity in the first second will be evaluated |
| pulmonary parameter-Mid expiratory flow rate | before and after 8 weeks | Mid expiratory flow rate will be evaluated |
| Lipit profile-High density lipoprotein cholesterol | before and after 8 weeks | High density lipoprotein cholesterol wiil be assesed |
Countries
Turkey (Türkiye)
Outcome results
None listed