Diabetes Mellitus, Type 2
Conditions
Brief summary
Observational, retrospective study, conducted in diabetic patients aimed to evaluate the effects on the glyco-metabolic control and on cardiovascular events of different DPP-4 inhibitors. Patients will be stratified in patients taking different DPP-4 in addition to sulfonylureas, biguanides, thiazolidinediones, insulin, compared to those in therapy with other hypoglycemic classes, such as sulphonylureas, biguanides, thiazolidinediones, insulin, alone or in combination, in primary and secondary prevention.
Interventions
DRUGDPP-4 inhibitors
Patients will be retrospectively evaluated after the addition of a DPP-4 inhibitor to previously taken anti-diabetic therapy
Sponsors
University of Pavia
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Type 2 diabetic patients * On oral hypoglycemic agents ± basal insulin * In primary and secondary prevention
Exclusion criteria
\- Patients with a follow-up of less than 8 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glycated hemoglobin | 8 years | Percentage |
| Fasting plasma glucose | 8 years | mg/dl |
| Post-prandial plasma glucose | 8 years | mg/dl |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Atrial fibrillation | 8 years | Percentage |
| Fatal myocardial infarction | 8 years | Percentage |
| Non-fatal myocardial infarction | 8 years | Percentage |
| Heart failure | 8 years | Percentage |
| Angina pectoris | 8 years | Percentage |
| Extrasystoles | 8 years | Percentage |
| Cardiovascular death | 8 years | Percentage |
Countries
Italy
Outcome results
None listed