Dual Site-Dual Channel Non-invasive Brain Stimulation for Language and Cognitive Function in Healthy Subjects

Effect of Dual Site-Dual Channel Non-invasive Brain Stimulation for Recovery of Language and Cognitive Function in Healthy Subjects

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03486808

Enrollment

Registered

2018-04-03

Start date

2018-02-28

Completion date

2018-05-22

Last updated

2019-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

transcranial direct current stimulation, motor function

Brief summary

The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of language and cognitive function in healthy. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on left inferior frontal cortex, ii) anodal stimulation on left dorsolateral prefrontal cortex. 2) IFG stimulation: anodal stimulation on left inferior frontal cortex; 3) DLPFC stimulation: anodal stimulation on left dorsolateral prefrontal cortex area. 4) sham stimulation

Interventions

DEVICEIFG stimulation

stimulating left inferior frontal cortex with transcranial direct current stimulation for 30 minutes

DEVICEDLPFC stimulation

stimulating left dorsolateral prefrontal cortex with transcranial direct current stimulation for 30 minutes

DEVICESham stimulation

sham stimulation over both left inferior frontal cortex and dorsolateral prefrontal cortex

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* healthy subjects with age over 19 years old

Exclusion criteria

* history of disorders involving central nervous system * patients with severe medical or psychiatric disease

Design outcomes

Primary

Measure	Time frame	Description
Korean Boston naming test	Baseline and after intervention (approximately 30 minutes)	measures naming ability thorough picture naming test
Verbal 3 back test	Baseline and after intervention (approximately 30 minutes)	measure working memory

Secondary

Measure	Time frame	Description
Korean Color Word Stroop test	Baseline and after intervention (approximately 30 minutes)	measures selective attention and executive function
Controlled Oral Word Association Test	Baseline and after intervention (approximately 30 minutes)	measure verbal fluency

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026