Dual Site-Dual Channel Non-invasive Brain Stimulation for Motor Function in Healthy Subjects

Effect of Dual Site-Dual Channel Non-invasive Brain Stimulation for Recovery of Motor Function in Healthy Subjects

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03486795

Enrollment

Registered

2018-04-03

Start date

2017-10-31

Completion date

2018-05-10

Last updated

2019-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

transcranial direct current stimulation, motor function

Brief summary

The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in healthy subjects. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex, ii) anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area. 2) M1 stimulation: anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex; 3) PMC stimulation: anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area. 4) sham stimulation

Interventions

DEVICEM1 stimulation

stimulating primary motor cortex with anodal stimulation on right primary motor cortex and cathodal stimulation on left primary motor cortex

DEVICEPMC stimulation

stimulating premotor cortex with anodal stimulation on right premotor cortex and cathodal stimulation on left supraorbital area

DEVICESham stimulation

sham stimulation over both primary motor cortex and premotor cortex

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* healthy subjects with age over 19 years old

Exclusion criteria

* history of disorders involving central nervous system * patients with severe medial or psychiatric disease

Design outcomes

Primary

Measure	Time frame	Description
Changes in motor evoked potential	Baseline and after intervention (approximately 30 minutes)	measure the motor threshold and amplitude of motor evoked potential in first dorsal interosseous muscle

Secondary

Measure	Time frame	Description
Changes in sequential motor task	Baseline and after intervention (approximately 30 minutes)	measures motor functional and dexterity of hand

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026