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Urodynamics and Clinical Factors That Are Associated With Bladder Over-sensitivity

Urodynamics and Clinical Factors That Are Associated With Bladder Over-sensitivity

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03486639
Enrollment
330
Registered
2018-04-03
Start date
2017-07-01
Completion date
2020-08-19
Last updated
2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Prostate Enlargement, Bladder Disease, Bladder Outlet Obstruction, Overactive Bladder Syndrome, Stress Incontinence (Female) (Male)

Keywords

Urodynamics, Bladder sensation, confounding factors

Brief summary

Urodynamic examination evaluates storage and empting phases of the urinary bladder. It enables the clinician to correlate physiologic findings to patients' complains. The data gathered during the examination divided to storage and empting. During the storage phase, bladder sensation is measured while the bladder is filled with sterile water. During years of practice, we noticed that early sensation (bladder over-sensitivity) is occasionally associated with bladder outlet obstruction (as demonstrated in the emptying phase of the examination.

Detailed description

The study includes patients who were referred to Urodynamics examination due to lower urinary tract symptoms. There is no actual intervention during the examination. Though, patients are asked to fill an International prostate symptom score (IPSS-questionnaires).

Interventions

IPSS is an 8 question (7 symptom questions + 1 quality of life question) written screening tool used to screen for, rapidly diagnose, track the symptoms of, and suggest management of patients with lower urinary tract symptoms. It was validated for both genders.

Sponsors

Assaf-Harofeh Medical Center
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All patients refered to Asaf HaRofeh Medical Center for Urodynamic examination

Exclusion criteria

* Inability to sign an informed concent * Administration of analgesics 8 hours prior to the examination * Known urethral stricture * Chronic bladder or urethral pain * Active cystitis * Permanent urinary catheter

Design outcomes

Primary

MeasureTime frameDescription
Early sensation during the filling phaseDuring the urodynamic examinationBladder oversensitivity (early sensation), a diagnosis made by symptoms and urodynamic investigations. Defined as an increased perceived bladder sensation during bladder filling with specific cystometric findings of: (i) an early first desire to void; (ii) an early strong desire to void, which occurs at low bladder volume; (iii) a low maximum cystometric bladder capacity; no abnormal increases in detrusor pressure.

Countries

Israel

Contacts

Primary ContactGuy Verhovsky, MD
guy.verchovsky@gmail.com972-8-9779409

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026