Brugada Syndrome
Conditions
Brief summary
Although for many years the Brugada syndrome has been labelled as a purely electrical disease in the structurally normal heart, the evolution of imaging techniques has enabled the discovery of subtle morphofunctional alterations in some of the Brugada syndrome patients. We will use new echocardiographic techniques to assess cardiac function in these patients and new parameters will be evaluated for their prognostic value as risk stratificators.
Interventions
DIAGNOSTIC_TESTTransthoracic echocardiography
Transthoracic echocardiography Blood sample with assessment of biomarkers
Sponsors
Universitair Ziekenhuis Brussel
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* 18 years or older * Diagnosis of Brugada syndrome
Exclusion criteria
* history of pericarditis, ischemic heart disease, cardiomyopathy of any origin, structural heart disease, or any other channelopathy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Composed outcome of sudden cardiac death, appropriate ICD shock and witnessed ventricular fibrillation | 6 years | Sudden cardiac death is death occuring within 24 hours after being seen in a healthy status or within 1 hour after initiation of symptoms. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Syncope | 6 years | Loss of consciousness |
Countries
Belgium
Contacts
Primary ContactEsther Scheirlynck
Outcome results
None listed