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Femtosecond Laser Versus Microkeratome in Creating Corneal Flaps in LASIK

Predictability of Corneal Flap Thickness in Lasik Using Femtosecod Laser in Comparison to Moria Microkeratome

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03484468
Enrollment
50
Registered
2018-03-30
Start date
2018-04-30
Completion date
2020-04-30
Last updated
2018-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Femtosecond Laser in Comparison to Moria Microkeratome in Creating Corneal Flaps

Keywords

lasik, flap_thickness, femtosecond, laser, moria, microkeratome

Brief summary

Since the cornea is the main responsible for the refraction of the eye, as its refractive power is greater than 70% of the total refraction of the eye, so modification of its refractive properties are used to change the optical system of the eye. Hence, laser-assisted in situ keratomileusis has become the most commonly procedure used to correct the refractive errors of the eye. The most important step in laser-assisted in situ keratomileusis is the creation of the corneal flap, which its thickness may judge the whole outcome of the surgery . So trying to minimize the variation in the thickness of the resultant flap in comparison to what planned flap thickness preoperatively become our target.

Detailed description

As laser-assisted in situ keratomileusis procedure started to use automated microkeratomes in creating corneal flaps since 1989, and science go on until United states Food and Drug Administration approved the IntraLase laser for flap creation in January 2000 femtosecond lasers work by emitting light pulses of short duration (10-15 s) at 1053 nm wavelength that cause photodisruption of the tissue with minimum collateral damage . This enables no blade incisions to be performed within the tissue at various patterns and depth with high precision. Aim of the work To evaluate and compare the variation in corneal flap thickness created from use of a femtosecond laser and a MORIA microkeratome when making a 110-µm- and 90- µm thick corneal flap and to identify the potential factors that affect corneal flap thickness.

Interventions

DEVICEanterior segment Ocular Coherence Tomography

anterior segment OCT (Ocular Coherence Tomography) a device shows imaging of anterior segment of the eye and able to show corneal layers and measures its thickness.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Age 18-40 year * Preoperative spherical refraction of -2.00 to -10.00D. * Refractive cylinder of less than -3.00D. * A stable refractive state for 2 years. * An intraocular pressure (IOP) of \<22 mm Hg.

Exclusion criteria

* A history of any systemic autoimmune disease. * A history of diabetes. * Other ophthalmic disorders. * A history of ocular trauma and surgical history.

Design outcomes

Primary

MeasureTime frameDescription
corneal flap thickness7 daysmeasuring the corneal flap thickness in nanometers postoperatively by anterior segment OCT

Secondary

MeasureTime frameDescription
uncorrected visual acuity7 daysidentifying uncorrected visual acuity postoperatively
best corrected visual acuity7 daysidentifying best corrected visual acuity postoperatively

Contacts

Primary ContactSAMIR Y. SALIH, PHD
samir.abouelail@med.au.edu.eg+201003304320
Backup ContactHANY O. EL-SEDAFE, PHD
helsedfy@aun.edu.eg+201005263681

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026