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Long Thoracic Nerve Blockade for Pain Treatment After Video-Assisted Thoracoscopic Surgery

Investigation of Analgesic Effect of Long Thoracic Nerve Blockade After VATS (Video-Assisted Thoracoscopic Surgery) Operation

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03483415
Enrollment
60
Registered
2018-03-30
Start date
2018-05-01
Completion date
2019-04-01
Last updated
2018-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nerve Block, Video-Assisted Thoracic Surgery

Brief summary

Video-assisted thoracoscopic surgery (VATS) provides an opportunity to penetrate the thoracic cavity by video through an incision into the chest wall and facilitate surgical operation of lung pathologies.Various regional methods of anesthesia are currently being used to achieve this goal. The aim of the study was to assess the effectiveness of Long thoracic nerve bloc on postoperative VATS analgesia.

Interventions

DRUGMorphine Sulfate

Intravenous morphine infusion with PCA: Solution was concentration of 0.5 mg/mL. Loading dose of 1 mg, 0.5 mg of bolus dose and 20 min of locking time.

DRUGBupivacaine

Ultrasound guided Long thoracic nerve blockage with 5 ml % 0.25 bupivacaine

Sponsors

Bursa Yuksek Ihtisas Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Intervention model description

Prospective, randomized, controlled, single-blind

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Patients who were in the American Society of Anesthesiologists (ASA) I-III class and underwent video-assisted thoracoscopic surgery (VATS).

Exclusion criteria

* Previous history of opioid use preoperatively, * Allergy to local anesthetics, * The presence of any systemic infection, * Uncontrolled arterial hypertension, * Uncontrolled diabetes mellitus.

Design outcomes

Primary

MeasureTime frameDescription
morphine consumptionPostoperative 24 hoursmorphine consumption

Secondary

MeasureTime frameDescription
Visual Analog ScalePostoperative 24 hoursVisual Analog Scale was used for pain.Pain intensity was measured using 0-10 cm visual analogue scale (VAS). (0=no pain, 10=intolerable pain)
side effect (Hypotension)Postoperative 24 hoursside effect Hypotension
additional analgesic usePostoperative 24 hoursadditional analgesic use
side effect (Nausea and vomiting)Postoperative 24 hoursNausea and vomiting scale 1\. Nausea and vomiting scale (nausea-vomiting scale (NVS): 1. No nausea is present, 2. Mild nausea is present. 3. Severe nausea is present. 4. Vomiting is present) In case of a NVS score of \>3, an anti-emetic drug was administered.
side effect (Ramsay Sedation Scale (RSS)Postoperative 24 hoursRamsay Sedation Scale (Ramsay Sedation Scale (RSS) : 1. Anxiety, agitation are present; 2. Cooperated, awake; 3. Sedatized, response to commands; 4. Sleepy, immediately awoken by auditory stimulus or glabella tap; 5. Sleepy, deep response to auditory stimulus or glabella tap and 6. Sleepy, no response to auditory stimulus or glabella tap)

Contacts

Primary Contactkorgün Ökmen, M.D
korgunokmen@gmail.com+902242955000
Backup ContactBurcu Metin Ökmen, M.D
burcumetinokmen@gmail.com+902242955000

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026