Psoriasis
Conditions
Brief summary
• Assessment of tissue level of resolvin D1 in psoriasis in comparison to its level in healthy controls in order to verify its role in the pathogenesis of psoriasis.
Interventions
skin biopsy before and after NB-UVB phototherapy to measure tissue resolvin D1
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients with psoriasis (adults and children above 12years) * Both sexes. * New cases or cases not receiving any treatment for at least 3 months ago.
Exclusion criteria
* Any contraindication to phototherapy treatment (e.g. Photosensitizing creams or medications, past skin cancer, especially melanoma, etc...) * Erythrodermic and pustular psoriasis. * History of autoimmune diseases or other systemic diseases (e.g. Alzheimer's disease, fibromyalgia, cystic fibrosis)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tissue levels of resolvin D1 in psoriatic patients before and after NB-UVB. | 6 months |
Countries
Egypt