Comparison of Erector Spinae Plane Block With Thoracic Paravertebral Block for Breast Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03480958

Enrollment

Registered

2018-03-29

Start date

2018-03-28

Completion date

2018-08-20

Last updated

2018-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer, Postoperative Pain

Keywords

erector spinae plane block, thoracic paravertebral block, breast surgery, postoperative pain

Brief summary

Postoperative analgesia in breast surgery is a difficult and overworked issue due to etensive surgery and complex innervation of the breast. Erector spinae plane block (ESB) is a new defined and promising regional anesthesia technique for thoracic analgesia. Main purpose of this study is to compare the analgesic effect of ultrasound guided ESB with thoracic paravertebral block - the golden standard method for postoperative regional analgesia technique in breast surgery.

Interventions

DEVICEIntravenous morphine patient controlled device

24 hour morphine consumption will be recorded

OTHERErector Spinae Plane Block

erector spinae plane block will be administered before the surgery

OTHERThoracic Paravertebral Block

thoracic paravertebral block will be administered before the surgery

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 70 Years

Healthy volunteers

Inclusion criteria

* 25-70 years of agge * ASA I-II * Undergoing elective breast cancer surgery

Exclusion criteria

* obesity (body mass index \>35 kg/m2) * infection of the skin at the site of needle puncture area * patients with known allergies to any of the study drugs * coagulopathy * recent use of analgesic drugs

Design outcomes

Primary

Measure	Time frame	Description
Morphine consumption	24 hour postoperatively	All patients will be provided with IV morphine PCA and morphine consumption after 24 hour postoperatively will be recorded.

Secondary

Measure	Time frame	Description
Numering Rating Scale scores for pain	24 hour	Numeric Rating Scale (NRS) for pain will be used. The Numeric Rating Scale (NRS-11) is an 11-point scale for patient self-reporting of pain. It is for adults and children 10 years old or older. 0 means no pain and 10 means most imaginable pain
Postoperative nausea and vomiting	24h	Incidence of postoperative nausea and vomiting will be recorded

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 2, 2026