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Diaphragm Ultrasound to Predict Weaning Outcomes in Mechanically Ventilated Patients

Diaphragm Ultrasound to Predict Weaning Outcomes in Mechanically Ventilated Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03480828
Enrollment
36
Registered
2018-03-29
Start date
2017-04-01
Completion date
2017-12-31
Last updated
2018-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Accuracy of DE and DTF in Prediction of Extubation Success

Brief summary

This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation.

Detailed description

This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation. The investigators compared the median values of DE and DTF in the group of successfully extubated patients and the group of patients who needed reintubation. Our study compared the utility of DTF and DE to predict extubation success.

Interventions

DIAGNOSTIC_TESTcomparaison between DE and DTF in prediction of extubation success

diaphragm ultrasound and measurement of DE and DTF in patients meeting all extubation criteria during spontaneous breathing trial

Sponsors

Mongi Slim Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients who were mechanically ventilated for more than 48h and meeting all criteria for extubation * patients without history of neuromuscular disease, or severe chronic respiratory failure

Exclusion criteria

* patients who needed reintubation for upper airway obstruction or neurological or hemodynamic instability

Design outcomes

Primary

MeasureTime frameDescription
extubation success48 hours after extubationcomparaison between DE and DTF values in successfully extubated patients

Countries

Tunisia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026