Thyroid Neoplasms
Conditions
Brief summary
Purpose: Total endoscopic thyroidectomy including oral approach and breast approach has excellent cosmetic and several functional results. Many patients, especially women, undergoing thyroid surgery are concerned about the postoperative cosmetic appearance of the neck. The procedure of total endoscopic thyroidectomy by breast approach only left three incisions, while by oral approach did not leave any incisions in the body surface, which is scarless in the neck, involved with a higher cosmetic result. However, the long-term property evaluation of total endoscopic thyroidectomy was not confirmed. The purpose of our study was to evaluate the surgical results of total endoscopic thyroidectomy (transoral approach and breast approach) versus conventional open thyroidectomy.
Detailed description
Purpose: Total endoscopic thyroidectomy including oral approach and breast approach has excellent cosmetic and several functional results. Many patients, especially women, undergoing thyroid surgery are concerned about the postoperative cosmetic appearance of the neck. Transoral endoscopic thyroidectomy via vestibular approach (TOETVA) and endoscopic thyroidectomy via breast approach were routinely performed in our institute. The procedures of total endoscopic thyroidectomy by breast approach only left three incisions, while by oral approach did not leave any incisions in the body surface, which is scarless in the neck, involved with a higher cosmetic result. However, the comprehensive comparison between transoral approach, breast approach and conventional open method was not confirmed. The purpose of our study was to evaluate the surgical results of total endoscopic thyroidectomy (transoral approach and breast approach) versus conventional open thyroidectomy.
Interventions
PROCEDUREThyroid Surgical Methods
Different methods of thyroid surgery, including conventional open thyroidectomy, transoral endoscopic thyroidectomy via vestibular approach, and endoscopic thyroidectomy via breast approach.
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
15 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
1. Age: 15\ 55 years old; 2. Type: Differentiated thyroid carcinoma, diameter ≤ 2cm, cN0 or cN1a, M0; 3. Thyroid lobe was less than the second degree enlargement; 4. Thyroid benign goiter, and the diameter ≤ 6cm
Exclusion criteria
1. Combine the surgical history of mandibular, oral, facial, or neck; 2. It was shown by preoperative radiological examination that the thyroid cancer has local invasion, N1b, or distant metastasis. 3. Thyroid lobe was more than the third degree enlargement 4. Any medical history that probably interfere the test results or increase the disease risks 5. The patient's compliance is not very well, and cannot work as the doctors asked
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of life assessment postoperatively | 12 months after the surgery of thyroidectomy | Physicians Global Assessment to measure quality of life was performed, and the assessment form had been verified. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cosmetic results of thyroidectomy postoperatively | 12 months after the surgery of thyroidectomy | Visual Analog Score (1-10) for the cosmetic results (evaluated by patients) was been performed. |
| Surgical Complications of thyroidectomy postoperatively | 12 months after the surgery of thyroidectomy | The rates (percentage) of surgical complications (transient or permanent Recurrent Laryngeal Nerve paralysis, transient or permanent hypoparathyroidism, Postoperative hemorrhage) |
| Surgical Completeness of thyroidectomy postoperatively | 12 months after the surgery of thyroidectomy | The rates (percentage) of surgical completeness (whether or not any thyroid associated tissues left by the examination of ultrasound and Iodine-131) |
Countries
China
Contacts
Primary ContactYong Wang, MD.
Backup ContactXing Yu, MD.
Outcome results
None listed