Hypotension Drug-Induced
Conditions
Brief summary
To compare the effect of two different protocol of fluid therapy in sever preeclamptic patients under spinal anesthesia : Hemodynamic and kidney function .
Interventions
DRUGLactated Ringer
Patients will be divided into 2 groups according to the amount of fluids received during caesarian section under spinal anesthesia. Group (R) 30 patients will receive 15ml/kg/h lactated Ringer (LR) intraoperative. Group (L) 30 patients will receive 30ml/kg/h lactated Ringer (LR) intraoperative. blood loss will be replaced if more than 500 ml in ratio 3 ml crystalloid : 1ml blood in both groups
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* more than 36 weeks gestation * singleton pregnant women planned for elective caesarian section
Exclusion criteria
* patient refusal. * psychiatric disorders. * parturient \<36 weeks gestation, twins, abnormal cardiotocography (CTG) tracing. * absolute contraindications for spinal anesthesia (patients refusal, raised intracranial pressure, hypovolemic states, abnormal coagulopathy).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| incidence of hypotension | 1 hour | decrease in systolic blood pressure more than 20% of base line |
Contacts
Primary ContactZein El Abadin Zarae Hassan, PhD
Outcome results
None listed