Ultrasound Guided Supraclavicular Brachial Plexus Block, Volume Comparison of Local Anaesthetics and Diaphragmatic Motility.

Effects of Various Volume of Local Anaesthetic Use for Ultrasound Guided Supraclavicular Brachial Plexus Block on Successful Blockade and Diaphragmatic Motility.

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03476694

Enrollment

Registered

2018-03-26

Start date

2018-07-01

Completion date

2019-02-01

Last updated

2018-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sucessful Block With Less Hemidiaphragmatic Paresis in Distal Upper Arm Fracture

Brief summary

Brachial plexus block as done by landmark technique use large volume of local anaesthetics (at least 30-40 ml), leading to higher incidence of phrenic nerve involvement and diaphragmatic dysfunction. With use of ultrasound dose of local anaesthetic can be reduced. Volume as low as 20 ml when use by ultrasound guidance has shown to provide successful block with no hemidiaphragmatic palsy when compared with nerve stimulation technique. But no study has compared the different volumes of drug on success rate and diaphragmatic motility.So in this study , the investigators want to compare the incidence of hemidiaphragm paralysis and success of block with different volumes of local anaesthetic , so that the lowest effective dose with higher safety profile can be determined.

Interventions

PROCEDUREultra sound guided supraclavicular brachial plexus block

ultra sound guided supraclavicular brachial plexus block , comparing the volume of 0.75 % ropivacine in sucessful block and hemidiaphragmatic motilty.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

Inclusion * Age between 18 and 60 years undergoing distal arm surgery * American Society of Anesthesiologists physical status 1 to 3 * Able to give informed consent * Body weight greater than 50 kg Exclusion * Patient refusal for supraclavicular block. * Inability to obtain informed consent. * Contraindication to Brachial plexus block * Pulmonary and cardiac disorders * Pregnancy * Allergy to local anesthetic * Chest or shoulder deformities

Design outcomes

Primary

Measure	Time frame	Description
hemidiaphragmatic paralysis	within 30 minutes after sucessfull blocade	grading of hemidiaphragmatic paralysis as, complete ,partial and no hemidiaphragmatic paralysis as reduction of diaphragmatic excursion greater than 75%, 25-75%, less than 25% respectively after sucessful blocade.

Secondary

Measure	Time frame	Description
sucessful blocade	within 30 minutes of block	ultrasound guided supraclavicular brachial plexus block using ropivacine and observing the complete block.

Countries

Nepal

Contacts

Primary Contactshambhu adhikari, md resident

smvuadhikari@gmail.com9779841104097

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026