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Coagulopathy in Cardiac Surgery

Coagulopathy in Cardiac Surgery; a Quaternary-care Academic Center Experience

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03475940
Enrollment
398
Registered
2018-03-23
Start date
2017-12-31
Completion date
2020-06-30
Last updated
2020-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coagulopathy, Cardiac Surgery, Cardiopulmonary Bypass

Brief summary

Coagulopathy in cardiac surgery; a quaternary-care academic center experience Objectives: Primary: To determine incidence of coagulopathy after cardiac surgery in Thai people To determine incidence of resternotomy for stop bleeding, morbidity and mortality Secondary: To identify risk factors which associated with non-red cell transfusion and coagulopathy study decide: Retrospective chart review

Detailed description

Data to be collected: Age\*, gender\* Body weight, height, body mass index\* Underlying disease: DM, renal disease\*, liver disease\* Pre-op. Antiplatelet or anticoagulant\* Pre-op coagulogram and platelet count\* Emergency or elective surgery Resternotomy or not\* Intraoperative blood component Intraoperative factor concentration Dose and timing of antifibrinolytic administration\* CPB time\* Postoperative body temperature\* \*Possible risk factors for non-red cell transfusion statistic: To assess the relationship between risk factors and non-red cell transfusion a univariate analysis was performed using an unpaired t-test and a Chi-square test. For higher accuracy regarding the impact of single risk factors, a multiple logistic regression analysis was also performed.

Interventions

None listed

Sponsors

Mahidol University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Age ≥ 18 years * Schedule to cardiac surgery under cardiopulmonary bypass

Exclusion criteria

* Schedule for aortic surgery or complex congenital cardiac surgery * Using ECMO before surgery * Incomplete anesthetic record

Design outcomes

Primary

MeasureTime frameDescription
incidence of coagulopathy after cardiac surgery in Thai people1 yearcoagulopathy and throbocytopenia

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026