Renal Infarction
Conditions
Brief summary
Kidney Magnetic Resonance assessment before and after undergoing transcatheter aortic valve replacement
Detailed description
Each patient will undergo Magnetic Resonance assessment of the kidneys before the TAVR. on the third to 7th day after the ATVR, a second MRI to the kidneys will be performed. we will assess the changes and new lesions between both MRI tests and will perform a qualitative and quantitative measurement.
Interventions
DIAGNOSTIC_TESTMagnetic Resonance test for kidney
Magnetic Resonance test for kidney
Sponsors
Sheba Medical Center
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* Severe symptomatic aortic stenosis * Patient is able to lay down supine for 20 min (the time needed to perform the MRI) without any difficulties.
Exclusion criteria
* Patient is on chronic renal replacement therapy (Dialysis) * Documented Thrombus in the left ventricle or left atria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| New Renal Infarction | one year | New low signal intensity lesions on diffusion weighted images on MRI. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hematuria | one year | New hematuria on urine test. |
| Elevation in Blood Pressure | one year | Delta of more than 5% |
| Elevation in Plasma Renin Activity | one year | Delta of more than 5% |
| Elevation in Aldosteron level | one year | Delta of more than 5% |
Countries
Israel
Contacts
Primary ContactArwa Younis, Doctor
Outcome results
None listed