Developing Non-Communicable Disease Registries in Africa : A Step Towards Providing Quality Data for Improving Patient Outcomes

Developing Non-Communicable Disease Registries in Africa: A Step Towards Providing Quality Data for Improving Patient Outcomes

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03473795

Enrollment

6990

Registered

2018-03-22

Start date

2018-03-16

Completion date

2027-03-01

Last updated

2026-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-Communicable Disease

Keywords

Patient Outcomes, 18-114

Brief summary

This umbrella protocol seeks to develop robust data registries for non-communicable diseases (NCDs) in sub-Saharan Africa (SSA) with the aim of providing accurate and comprehensive data for the evaluation of such diseases in sub-Saharan African countries.Healthy volunteers will be included in the study for comparison. Additionally, the investigators aim to describe the gut microbiome community diversity of a cohort of community dwelling Nigerians and compare with CRC patients in Nigerian and at MSK. We will collect stool for microbiome and metabolomic analysis from community dwelling persons in the catchment area of ARGO facilities in Nigeria while contemporaneously administering an extensive medical and environmental exposure questionnaire.

Interventions

BEHAVIORALQuestionnaire forms

The questionnaires will include information such as socio-demographic data, risk factors, disease specific data, investigation and treatment details as well as findings during followup. Particular reference will be made to outcome measures such as local and distant recurrence, survival and mortality.

OTHERBio-specimen samples

Samples can include tissue, blood, urine, saliva, hair and nail clipping.

Study design

Observational model

ECOLOGIC_OR_COMMUNITY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Age 18 and older. * Suspected or confirmed diagnosis of a non-communicable disease. OR * Healthy volunteers/no confirmed diagnosis for comparison.

Exclusion criteria

* Participants unwilling to sign consent. * Participants under the age of 18

Design outcomes

Primary

Measure	Time frame
# of patients that develope non-communicable diseases in Africa	5 years

Countries

Nigeria, United States

Contacts

PRINCIPAL_INVESTIGATORT. Peter Kingham, MD

Memorial Sloan Kettering Cancer Center

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 19, 2026