Skip to content

One-stage Exchange Arthroplasty for Chronic Prosthetic Joint Infections

One-stage Exchange Arthroplasty for Chronic Prosthetic Joint Infections

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03473392
Enrollment
13
Registered
2018-03-22
Start date
2016-04-30
Completion date
2018-01-31
Last updated
2018-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exchange of Prosthetic Joint, One-step Exchange, Prosthetic Joint Infection

Keywords

pre-treatment, antibiotherapy, prosthetic joint infection, treatment failure

Brief summary

The results found in the literature do not allow to define objectively the indications respective for a one-step or a two-step exchange of prosthetic joint. Some criteria could help to decide for one-step exchange or two-step exchange: bacteria is/are identified, profile of the bacteria, anesthetic difficulties,.. A puncture could allow to identify the bacteria involved in the prosthetic joint infection (PJI) and an antibiotherapy for a few days can be given to the patient in order to decrease the inoculum. Then, a one-step exchange can be performed. The purpose of this study is to describe the management of patients who had a pre-treatment before a one-step exchange of their prosthetic joint.

Interventions

None listed

Sponsors

Hospices Civils de Lyon
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patient with prosthetic joint infection and having had a pre-treatment, managed at the Croix-Rousse Hospital * \> 18 years old

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
bacterial epidemiologyat the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption)This outcome will describe the bacterial epidemiology identified with a punction, the antibiotherapy used for pre-treatment, the characteristics of patients and the PJI.

Secondary

MeasureTime frameDescription
Treatment failureat the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption)Treatment failure is defined by local clinical and/or microbiological relapse; and/or need for additional surgery; death of septic origin

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026