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Unilateral Posterolateral Approach for Spondylodiskitis

Unilateral Posterolateral Approach for Disc Debridement and Titanium Cage Insertion Supplemented by Contralateral Transfascial Screw Fixation for Sick Patients Suffering From Septic Thoracolumbosacral Spondylodiscitis

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03472131
Acronym
SPDTIS
Enrollment
20
Registered
2018-03-21
Start date
2004-01-31
Completion date
2016-12-31
Last updated
2018-03-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Discitis

Keywords

Spondylodiscitis, Titanium Cage, Posterolateral Debridement, Immunosuppressed, Less Invasive, Spine Infection

Brief summary

This retrospective study assess the efficacy and safety of a posterolateral unilateral approach for debridement and titanium cage insertion supplemented by contralateral transfascial screw fixation for sick patients suffering from septic thoracolumbosacral spondylodiskitis. Hematogenous pyogenic spondylodiskitis requires surgical intervention in cases of development of neurological signs, spinal instability, progressive spinal deformity and abscess. When operative treatment is indicated, an anterior approach by open thoracotomy or by a thoraco-abdominal approach or combined anterior and posterior approaches are recommended. In cases of severe sick patients anterior approach is associated with high morbidity and mortality.

Detailed description

Twenty consecutive sick (ASA\>III) patients, 14 men and 6 women, aged 64±14 years, suffering from single level septic thoracolumbosacral spondylodiskitis underwent an one-stage less invasively unilateral posterolateral decompression, insertion of titanium cage& pedicle screw fixation plus contralateral transfascial pedicle screw fixation.

Interventions

PROCEDUREUnilateral Posterolateral Approach and Debridement
OTHERTitanium cage insertion supplemented by screw fixation

Sponsors

St. Andrew's General Hospital, Patras, Greece
CollaboratorOTHER
University Hospital of Patras
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
44 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Single-level thoracic, thoracolumbar, lumbar or lumbosacral spondylodiskitis * Medical comorbidities were present in all 20 patients. These included diabetes mellitus, chronic renal insufficiency, advanced heart insufficiency, hypertension, cortisone abuse, drug abuse and/or advanced age (\>65y).

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
The extent of spinal cord injury (SCI) defined by the American Spinal Injury Association (ASIA) Impairment Scale2 yearsGrade A Complete lack of motor and sensory function below the level of injury (including the anal area) Grade B Some sensation below the level of the injury (including anal sensation) Grade C Some muscle movement is spared below the level of injury, but 50 percent of the muscles below the level of injury cannot move against gravity. Grade D Most (more than 50 percent) of the muscles that are spared below the level of injury are strong enough to move against gravity. Grade E All neurologic function has returned.

Secondary

MeasureTime frameDescription
Survival rate at 2,5 years2,5 yearsRevision surgery or worst case scenario
Survival rate at 10 years10 yearsRevision surgery or worst case scenario

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 3, 2026