Superficial Colorectal Tumors
Conditions
Keywords
endoscopic resection, colorectal adenomas, Colorectal adenocarcinomas
Brief summary
To evaluate the long-term complete remission rate (\> 12 months) after endoscopic treatment of early neoplastic colorectal lesions.
Detailed description
Intra-mucous colorectal neoplasia lesions (or even with minimal mucosal infiltration), formerly treated surgically, are increasingly treated endoscopically. The IPC as a center for interventional endoscopy has been taking care of these lesions for several years. Resection techniques have diversified since the 2000s (polypectomy, monobloc or piecemeal mucosectomy, submucosal dissection ... etc) and the endoscopy team has developed its various techniques within the institute ; Practice has evolved and has not been studied or evaluated in recent years. The purpose of this study is to evaluate practices and to compare results with the literature, and to identify predictive factors for the failure or success of endoscopic treatment of these early neoplastic lesions.
Interventions
OTHEREvaluation of the long-term complete remission rate (> 12 months)
Evaluation of the long-term complete remission rate (\> 12 months)
Sponsors
Institut Paoli-Calmettes
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient having undergone endoscopic resection of a colorectal lesion stage 4 or 5 of the modified Vienna classification during the last 5 years at the institute.
Exclusion criteria
* Adenomas with low grade dysplasia * Endoscopic control not available
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Complete long-term remission (> 12 months) | 13 months | Evaluation of the long-term complete remission rate (\> 12 months) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rates of medium and long-term recurrence | 13 months | Recurrence rate in the medium and long term |
| Management of medium and long-term recurrence | 13 months | Management of recurrence (endoscopic revision or surgery) |
| Absence of residual lesion on early control (3 to 6 months) | 3 to 6 months | Medium-term response rate (3 to 6 months) |
| Lymph node or visceral metastatic evolution rate | 13 months | Rate of pejorative lymph node or metastatic evolution (especially for lesions with microinfiltration of the submucosa) |
| Endoscopic description and anatomopathological results | 1 day | Endoscopic and / or anatomopathological predictive factors of success (complete long-term remission) |
| Morbidity and mortality rates | 13 months | Morbidity and mortality rate of endoscopic resection |
Countries
France
Outcome results
None listed