Blood Glucose, High, Inflammation, Insulin Resistance, Obesity
Conditions
Keywords
Obesity
Brief summary
This study evaluates the effect of balanced and sustainable diet application on fat composition, insulin resistance and inflammation marker in obese people. Intervention: Obese subject will receive intervention on balanced and sustainable diet application Control: Obese subject will receive a balanced diet application only
Detailed description
Maintaining the adherence of weight loss programme while selecting healthy and sustainable foods will become a worldwide future challenge in nutrition. Therefore, we investigated the suitable content, graphic, and flow in developing a mobile application as an alternative solution for enhancing the compliance of weight control and selecting healthy food with the least environmental impact. The treatment for obesity consists of dieting, physical exercise, pharmacology, and surgery. Restricted balanced diet is a well known diet recommendation for people with obesity. Sustainable diet is an alternative form of diet which contributes to healthy life and is protective of biodiversity. The main challenge in obesity management is the sustainability of weight loss programme. Mobile apps are an alternative solution for enhancing compliance.
Interventions
OTHERbalanced and sustainable diet
the intervention group will get menu recommendation of restriction calorie balanced and sustainable diet for 8weeks. the other group will get menu recommendation of balanced diet for 8 weeks. these menus are given in the apps named EatsUp. the intervention group will get menu recommendation of restriction calorie balanced and sustainable diet for 8 weeks. the other group will get menu recommendation of balanced diet for 8 weeks. these menus are given in the apps named EatsUp.
Sponsors
Fakultas Kedokteran Universitas Indonesia
Indonesia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Masking description
Giving a spesific personal menu through android apps, one group with balance diet menu, and the other with balance and sustainable diet menu. Only di IT knows which person get which type of menu
Intervention model description
One group balance diet One group balance and sustainable diet
Eligibility
Sex/Gender
FEMALE
Age
19 Years to 59 Years
Healthy volunteers
Yes
Inclusion criteria
* Body mass index ≥ 25 kg/m2 * using Android-based smartphone * willing to join this research by signing informed consent
Exclusion criteria
* pale in physical examination * in weight loss program * have obesity with comorbidities * have hormonal diseases * consumed hormonal drug, PTU, anti diabetes drug * smoking or stop smoking under 2 years * pregnant and breastfeeding women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of body weight | baseline at Day0 and endline at Day56 | Change from baseline body weight at 8 weeks, is measured in kg |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change of Fasting plasma glucose | baseline at Day0 and endline at Day56 | Change from baseline Fasting plasma glucose at 8 weeks, is measured in mg/dL |
| Change of TNF alpha | baseline at Day0 and endline at Day56 | Change from baseline TNF alpha at 8 weeks, is measured in pg/ml |
| Change of Fasting Insulin | baseline at Day0 and endline at Day56 | Change from baseline Fasting Insulin at 8 weeks, is measured in µU/mL |
| Change of HOMA-IR | baseline at Day0 and endline at Day56 | Change from baseline HOMA-IR at 8 weeks, is measured using formulation : glukosa (mg/dL) x insulin (µU/mL)/405 |
| Change of Fat Mass | baseline at Day0 and endline at Day56 | Change from baseline Fat Mass at 8 weeks, is measured by body composition analyzer in kg |
| Change of Carbohydrate intake | baseline at Day0 and endline at Day56 | Change from baseline Carbohydrate intake at 8 weeks, is measured in gram using 24HR-recall |
| Change of Fat intake | baseline at Day0 and endline at Day56 | Change from baseline Fat intake at 8 weeks, is measured in gram using 24HR-recall |
| Change of Protein intake | baseline at Day0 and endline at Day56 | Change from baseline Protein intake at 8 weeks, is measured in gram using 24HR-recall |
| Change of Waist Circumference | baseline at Day0 and endline at Day56 | Change from baseline Waist Circumference at 8 weeks, is measured in cm |
Countries
Indonesia
Outcome results
None listed