Long-term Follow up After SG vs RYGB vs OAGB

Long-term Follow up After Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass Versus One-Anastomosis Gastric Bypass: A Comparative Study of Weight Loss

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03467646

Enrollment

600

Registered

2018-03-16

Start date

2010-06-30

Completion date

2017-12-31

Last updated

2018-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Weight Loss

Brief summary

A prospective randomized clinical study of all morbidly obese patients undergoing SG, RYGB and OAGB, as primary bariatric procedures, was performed. Patients were randomly assigned into 3 groups: those patients undergoing SG, those ones undergoing RYGB and those ones undergoing OAGB. BMI, excess BMI loss (EBMIL) and remission of type 2 diabetes (T2DM), hypertension (HT) and dyslipidemia (DL) were assessed.

Detailed description

A prospective randomized clinical study of all morbidly obese patients undergoing SG, RYGB and OAGB, as primary bariatric procedures, was performed. Patients were randomly assigned into 3 groups: those patients undergoing Sleeve Gastrectomy, those ones undergoing Roux-en-Y Gastric Bypass and those ones undergoing One-Anastomosis Gastric Bypass. Body Mass Index (BMI), excess BMI loss (EBMIL) and remission of type 2 diabetes (T2DM), hypertension (HT) and dyslipidemia (DL) were assessed.

Interventions

PROCEDURESleeve Gastrectomy

The patients undergo a Sleeve Gastrectomy as bariatric procedure

PROCEDURERoux-en-Y gastric bypass

The patients undergo a Roux-en-Y gastric bypass as bariatric procedure

PROCEDUREOne-Anastomosis Gastric Bypass

The patients undergo a One-Anastomosis Gastric Bypass as bariatric procedure

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* body mass index (BMI) \>40 Kg/m2 * BMI \> 35 Kg/m2 with the presence of comorbidities associated to obesity * age older than 18 years * Patients willing to participate in the study and giving their written consent

Exclusion criteria

* patients undergoing other bariatric techniques than SG, RYGB and OAGB * Patients undergoing any other surgical procedure added to the bariatric surgery * patients with medical or surgical pathologies that at the discretion of the investigators do not allow their participation in the study * inability to understand the nature and purpose of the study and / or to accept written participation in the study * impossibility to comply with pre-established clinical follow-up.

Design outcomes

Primary

Measure	Time frame	Description
Weight loss	1 , 2 and 5 years after surgery	The postoperative weight loss is investigated at 1, 2 and 5 years after surgery

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 6, 2026