BRUSH Sign: Radiolographic Marker of Cerebral Infarctus Prognosis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03467269

Enrollment

250

Registered

2018-03-15

Start date

2017-02-24

Completion date

2017-06-30

Last updated

2018-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Infarction

Brief summary

Today the treatment of ischemic stroke in acute phase is based on medicinal or endovascular revascularization. Cerebral MRI sequences help the diagnostic. This procedure uses deoxyhemoglobin as an endogenous tracer. This is also a scorer of cerebral ischemia and the increase lets visualized transcerebral veins in the suffering zone giving a brush aspect. Several studies show the interest of this sign and conclude that deoxyhemoglobin presence is a predictive factor of cerebral ischemia. The aim of the study is to evaluate this brush-sign and correlate it with the prognosis retrospectively.

Interventions

DIAGNOSTIC_TESTBrush sign

presence of a brush sign in MRI image in acute cerebral ischaemia

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* age\>18 years old * hospitalized for cerebral infarction * MCA territory * MRI within 24hours * Sequence of magnetic susceptibility (SWAN)

Exclusion criteria

* Incomplete cerebral infarct * MRI not possible

Design outcomes

Primary

Measure	Time frame	Description
autonomy level	Month 3	measurement of autonomy level by mRS

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026