Alcohol Drinking, Alcohol; Harmful Use, Alcohol Intoxication, Alcoholism, Alcohol Use Disorder, Binge Drinking
Conditions
Brief summary
This study aims to identify risk factors that prospectively predict alcohol problems in young adults.
Detailed description
The vast majority of alcohol use takes place in social settings, yet nearly all human experimental work has administered alcohol to individuals in isolation. This study will examine the effects of alcohol in social groups and test whether these responses predict the escalation of alcohol use and development of alcohol use disorder symptoms. Participants will also complete smartphone surveys querying subjective responses to alcohol in their daily lives. N=400 male and female young adults will participate in a laboratory session with two other participants and will consume either a moderate dose of alcohol or placebo beverage. Subjective and objective responses to alcohol will be assessed. Participants will also complete surveys on their smartphones; these will occur during drinking episodes and at random times throughout the day. Follow-up sessions will occur at 6-months and 12-months, to collect information about drinking habits and potential alcohol-related problems.
Interventions
DRUGAlcohol
target BAC .08%
OTHERPlacebo
placebo beverage
Sponsors
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
University of Pittsburgh
Penn State University
Carnegie Mellon University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
21 Years to 29 Years
Healthy volunteers
Yes
Inclusion criteria
* 21 to 29 years of age * currently drinks alcohol * owns a smartphone
Exclusion criteria
\[
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from Baseline Alcohol Use at 12-months | 12-month follow-up | Timeline Follow Back Method |
| Change from Baseline Alcohol Use Disorder Symptoms at 12-months | 12-month follow-up | Structured Clinical Interview for DSM-5 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Subjective Responses to Alcohol | 1 day (laboratory session) and 21-day ambulatory assessment period | Participants will indicate how they feel after drinking alcohol using the Brief-Biphasic Alcohol Effects Scale, which is a 6-item scale assessing alcohol's acute stimulant and sedative effects (0-10 scale, with higher scores indicating higher values). |
| Social Bonding | 1 day (laboratory session) | Facial expressions of emotions using Paul Ekman's Facial Action Coding System (FACS). The duration of AUs associated with positive and negative affect will be coded. |
| Mood | 1 day (laboratory session) | 8-item Mood Measure, which is an 8-item scale assessing mood items from each of the four quadrants of the affective circumplex (with higher scores indicating more felt emotion). |
| Alcohol Use | 21-day ambulatory assessment period | Quantity of standard drinks consumed. |
Countries
United States
Outcome results
None listed