Atrial Fibrillation, Death, Stroke, Acute
Conditions
Brief summary
The purpose of the research is to identify the frequency and severity of adverse events related to atrial fibrillation that occur after discharge from hospital where the patient underwent cardiac surgery. The Specific Aims of the proposed study are to: 1. Identify the predictors of postoperative atrial fibrillation after discharge from hospital. 2. Identify the frequency of readmission to hospital, or other resource use such as Emergency Department or outpatient visit, for the treatment or prophylaxis of postoperative AF and consequent stroke or bleeding outcomes. 3. Identify the risks for stroke, death and other morbidity in patients after cardiac surgery and the effect of postoperative AF upon subsequent stroke or bleeding outcomes.
Interventions
PROCEDURECardiac surgery
Retrospective cohort study
Sponsors
Beth Israel Deaconess Medical Center
Massachusetts General Hospital
Baystate Medical Center
Cape Cod Hospital
Mount Auburn Hospital
Memorial University Medical Center
Tufts Medical Center
St. Elizabeth's Medical Center
SouthCoast Medical Group
Brigham and Women's Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* Patients who underwent cardiac surgery in Massachusetts between 2012 - 2016
Exclusion criteria
* surgical procedures that do not include coronary artery bypass graft surgery, aortic valve surgery or mitral valve surgery; * surgical procedures that include MAZE surgery, or pulmonary vein isolation, ventricular assist device, heart transplantation, congenital heart surgery, bacterial endocarditis, cardiac trauma, cardiac tumor, ventricular septal defect repair, left ventricular aneurysm repair, pulmonary thromboendarterectomy, sub-aortic stenosis resection or surgical ventricular restoration; * surgical procedures on patients that have undergone MAZE surgery, AF ablation procedures, pulmonary vein isolation or left atrial appendage resection or ablation (such as Watchman devices).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recurrent atrial fibrillation | Up to six years after surgery | Recurrent atrial fibrillation |
| Acute ischemic stroke | Up to six years after surgery | Acute ischemic stroke |
| Mortality | Up to six years after surgery | Mortality |
Countries
United States
Contacts
Primary ContactJochen D Muehlschlegel, MD, MMSc
Outcome results
None listed